发明名称 |
MANUFACTURE OF LONG TERM DRUG DELIVERY DEVICES WITH POLYURETHANE BASED POLYMERS |
摘要 |
This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects, comprises: 1. a reservoir, said reservoir comprising: 2. at least one active ingredient; and 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir. |
申请公布号 |
CA2437639(A1) |
申请公布日期 |
2005.02.11 |
申请号 |
CA20032437639 |
申请日期 |
2003.08.18 |
申请人 |
VALERA PHARMACEUTICALS, INC. |
发明人 |
KUZMA, PETR;KUO, SHENG-HUNG |
分类号 |
A61K9/00;A61K9/22;A61K9/26;A61K9/70;A61L27/18;A61L27/54;C08J5/00;(IPC1-7):A61L27/18 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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