摘要 |
<P>PROBLEM TO BE SOLVED: To provide an anti-periodontal disease medicine which inhibits the activity of a trypsin-like protease produced by Porphyromonas gingivalis, further inhibits the activities of the trypsin-like protease and a collagenase produced by the bacterium, and can effectively prevent and treat the periodontal disease. <P>SOLUTION: This anti-periodontal disease medicine contains an extract which is obtained by extracting Ganoderma lucidum and/or Ganoderma atrum and has an action for inhibiting the activity of a trypsin-like protease produced by Porphyromonas gingivali, as an active ingredient. The anti-periodontal disease medicine contains an extract which is obtained by extracting Ganoderma lucidum and/or Ganoderma atrum and has an action for inhibiting the activity of the trypsin-like protease and a collagenase produced by the bacterium, as an active ingredient. <P>COPYRIGHT: (C)2005,JPO&NCIPI |