BENZOXAZEPINE COMPOUND

摘要

A compound represented by the formula [I]: [I] (wherein ring A and ring B ea ch represents an optionally substituted benzene ring; ring C represents an optionally further substituted aromatic ring; R1 represents a lower alkyl optionally substituted by optionally substituted hydroxy; X1a represents a bond or optionally substituted lower alkylene; X1b represents a bond or optionally substituted lower alkylene; X2 represents a bond, -O-, or -S-; X3 represents a bond or an optionally substituted divalent hydrocarbon group; a nd Y represents optionally esterified or amidated carboxy) or a salt of the compound. The compound of the formula [I] is safer and has more potent lipid - lowering activity such as squalene synthase inhibitory activity (cholesterol - lowering activity) and triglyceride-lowering activity. The compound is usefu l as a medicine for, e.g., the prevention of and treatments for hyperlipemia.< /SDOAB>