摘要 |
Compounds represented by the general formula (1) or pharmaceutically acceptable salts thereof; and antioxidants, remedies for kidney diseases or cerebrovascular disorder, or retinal oxidative damage inhibitors, containing the compounds as the active ingredient: B - D - Z (1) wherein B is a group represented by the following general formula (B-1), (B-2), or (B-3): A is optionally substituted imidazolyl or pyrazolyl; E is a group represented by the general formula (1a) or the like: (1a) X is O, SOu, or N-R9; Y is carbon or nitrogen; D is oxygen, sulfur, or a group of the general formula (1a); Z is an NHR10- or OR11-substituted, chroman-2-yl, chroman-4-yl, 2,3-dihydro- benzofuran-2-yl, or 2,3-dihydrobenzofuran-3-yl group or the like.
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申请人 |
NIPPON SODA CO., LTD. |
发明人 |
SHIRATO, FUMIE;IKEYAMA, SEIICHI;TSUBOKURA, SHIRO;SHIINOKI, YASUYUKI;UMEDA, NOBUHIRO;MOCHIZUKI, NOBUO;UCHIDA, SEIICHI;TAKADA, MITSUMASA;MOROE, HIROKO |