发明名称 6-MEMBERED HETEROARYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS
摘要 The present invention relates to compounds of the Formula wherein R1, R1a, R1b, R2,, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, X, Y, W, U, Z, m and n are as definited. Compounds of the Formula (I) have activity inhibiting production of A.beta.-peptide. This invention also relates to pharmatical compositions and methods of treating diseases, for example, neurodegenerativ e diseases, e.g., Alzheimer~s disease, in a mammal comprising compounds of the Formula (I).
申请公布号 CA2533554(A1) 申请公布日期 2005.02.10
申请号 CA20042533554 申请日期 2004.07.30
申请人 PFIZER PRODUCTS INC. 发明人 CHEN, YUHPYNG LIANG
分类号 C07D417/00;A61K;A61K31/4965;A61K31/501;A61K31/506;A61K31/52;C07D211/44;C07D211/54;C07D211/72;C07D215/10;C07D413/00;C07D417/04 主分类号 C07D417/00
代理机构 代理人
主权项
地址