Formulations and use of a beta-blocker and an ACE-inhibitor for the treatment of cardiovascular diseases

摘要

The use of a beta-blocker and an ACE-inhibitor in combination for the treatment of cardiovascular disorders, including hypertension and congestive heart failure, is provided. In particular, pharmaceutical formulations which use metoprolol tartrate and enalapril maleate in a therapeutically effective combination in a single extended release dosing unit for the treatment of congestive heart failure are disclosed as well as methods of using those formulations, thereby resulting in a decrease in a patient's overall pill burden.