IMMUNOMODULATION WITH NOVEL PHARMACEUTICAL COMPOSITIONS

摘要

The present invention relates to the synthesis and use of a novel class of tumor necrosis factor inhibitors and immunomodulators. These compounds have pharmacological applications as well as uses in assays relating to tumor necrosis factor and other involved cytokines. As pharmaceuticals, these compounds are used to treat inflammatory, infectious, autoimmune or other proliferative diseases and conditions related to the unwanted presence or activity of tumor necrosis factor and/or one or more other involved cytokine s, alone or in combination with other agents.