摘要 |
The invention provides a human TMPRSS2 which is associated with the cardiovascular disorders, endocrinological diseases, gastroenterological diseqases, metabolic diseases, cancer, respiratory diseases, urological disorders and inflammation. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, endocrinological diseases, gastroenterological diseqases, metabolic diseases, cancer, respiratory diseases, urological disorders and inflammation. The invention also features compounds which bind to and/or activate or inhibit the activity of TMPRSS2 as well as pharmaceutical compositions comprising such compounds. |
申请人 |
BAYER HEALTHCARE AG;GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS;POLEJ, STEFANIE |
发明人 |
GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS;POLEJ, STEFANIE |