СПОСОБ ВЫЯВЛЕНИЯ АНАЛИЗИРУЕМОЙ ПОСЛЕДОВАТЕЛЬНОСТИ ДНК

摘要

FIELD: molecular biology, medicine, pharmaceutical industry. ^ SUBSTANCE: method for detecting analyzed DNA sequence involves DNA hybridization with probes and visualization the prepared product wherein probes represent oligonucleotides with length of nucleotide sequence 12-30 nucleotides showing complementary to site of the same size in analyzed DNA that are modified with insertions based on alkyldiols or ethylene glycols. Applying the proposed method provides obtaining more reliable and selective results in detecting analyzed DNA sequences. ^ EFFECT: improved detecting method of DNA sequence. ^ 11 cl, 12 dwg, 13 ex