APOPTOSIS INDUCING GENE

摘要

Proteins which is involved in apoptosis, which are used for diagnosing, treating or preventing diseases associated with disorder of apoptosis, are provided. cDNAs encoding proteins having an activity of inducing apoptosis were cloned from the cDNA library constructed from Jurkat cell, ATDC5 cell and the like, and the DNA sequence and the deduced amino acid sequence were determined. The protein, the DNA encoding the protein, a recombinant vector containing the DNA, and a transformat containing the recombinant vector are used for screening a substance which inhibits or induces apoptosis.