| 发明名称 |
Process for the enantioselective preparation of secondary alcohols by lipase catalysed solvolysis of the corresponding acetoacetic acid ester |
| 摘要 |
<p>Enantioselective preparation of secondary alcohols (I), comprises enantioselective enzymatic solvolysis of a racemic or enantiomerically enriched mixture of acetoacetate esters (II) of chiral secondary alcohols in the presence of a nucleophile (III), using a lipase suitable for solvolytic cleavage of an ester group.</p> |
| 申请公布号 |
EP1505156(A1) |
申请公布日期 |
2005.02.09 |
| 申请号 |
EP20040017997 |
申请日期 |
2004.07.29 |
| 申请人 |
CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIE GMBH |
发明人 |
POPP, ALFRED, DR.;STOHRER, JUERGEN, DR.;PETERSEN, HERMANN, DR.;GILCH, ANDREA |
| 分类号 |
C07C27/02;C12P7/04;C12P7/20;C12P41/00;(IPC1-7):C12P41/00 |
主分类号 |
C07C27/02 |
| 代理机构 |
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