发明名称 Glucocorticoid receptor modulators
摘要 The present invention provides non-steroidal compounds of Formula I, including prodrugs and pharmaceutically acceptable salts thereof, which are selective modulators (e.g., agonists, partial agonists and antagonists) of a steroid receptor, specifically, the glucocorticoid receptor. The present invention also provides pharmaceutical compositions containing these compounds and methods for using these compounds to treat animals requiring glucocorticoid receptor agonist or antagonist therapy. Glucocorticoid receptor modulators are useful to treat diseases, such as obesity, diabetes, inflammation and others as described below. The present invention also provides processes for preparing these compounds
申请公布号 US6852719(B2) 申请公布日期 2005.02.08
申请号 US20010012274 申请日期 2001.10.26
申请人 PFIZER INC.;PFIZER PRODUCTS, INC. 发明人 LIU KEVIN K.;MORGAN BRADLEY P.;ROBINSON RALPH P.
分类号 A61K31/4245;A61K31/4439;A61K31/454;A61K31/5377;A61K45/06;A61P3/04;A61P3/10;A61P25/00;A61P25/22;A61P25/24;A61P29/00;C07D271/06;C07D413/04;C07D413/06;(IPC1-7):A61K31/424 主分类号 A61K31/4245
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