| 摘要 |
This invention relates to a method for the production of a sphingoid base according to formulacomprising the steps of(1) dissolving a starting compound according to formula III or a salt thereof in a substantially inert solvent,(2) protecting the NH2 group with a NH2 protecting group,(3) activating the C-4 HR<3 >group for an elimination reaction with the C-5 HR<4 >group,(4) causing an elimination reaction to take place to form a double bond between the C-4 and C-5 carbon atom, and(5) removing the NH2 protecting group.
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