| 发明名称 |
PULMONARY ADMINISTRATION OF CHEMICALLY MODIFIED INSULIN |
| 摘要 |
The present invention provides active, hydrophilic polymer-modified derivatives of insulin. The insulin derivatives of the invention are, in one aspect, suitable for delivery to the lung and exhibit pharmakokinetic and/or pharmacodynamic properties that are significantly improved over native insulin. |
| 申请公布号 |
PL366911(A1) |
申请公布日期 |
2005.02.07 |
| 申请号 |
PL20020366911 |
申请日期 |
2002.05.21 |
| 申请人 |
NEKTAR THERAPEUTICS;NEKTAR THERAPEUTICS AL,CORP. |
发明人 |
PATTON JOHN S.;KUO MEI-CHANG;HARRIS J.MILTON;LEACH CHESTER;PERKINS KIMBERLY;BUECHE BLAINE |
| 分类号 |
A61K9/08;A61K9/12;A61K9/19;A61K9/24;A61K9/72;A61K38/00;A61K38/16;A61K38/28;A61K47/34;A61K47/48;A61L9/04;A61P3/10;C07K14/62 |
主分类号 |
A61K9/08 |
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