COMPUESTOS DERIVADOS DE 7-AZA-QUINAZOLINA SUSTITUIDA, INHIBIDORES DE QUINASA P38; PROCEDIMIENTO DE PREPARACION; COMPOSICION FARMACEUTICA; Y SU USO PARA TRATAR ARTRITIS, ENFERMEDAD DE CROHN, ALZHEIMER, ASMA, ATAQUE AL CORAZON.

摘要

Compounds having the formula (I) or (II), are useful as p38 kinase inhibitors, wherein R is an optionally substituted alkyl, cycloalkyl, or aryl; R⁶ is hydrogen or lower alkyl; R⁷ is hydrogen or a non-interfering substituent, and Q is a non-aromatic moiety as defined in the specification.