发明名称 COMPUESTOS DERIVADOS DE BENZOTIAZOL SUSTITUIDOS CON DIOXANO, LIGANDOS DE RECEPTORES DE ADENOSINA, CON AFINIDAD CON LOS RECEPTORES A2A, A1 Y A3; COMPOSICION FARMACEUTICA; PROCEDIMIENTO DE PREPARACION; Y USO DE LOS COMPUESTOS EN EL TRATAMIENTO DE LA RE
摘要 The present invention relates to compounds of the general formula Iwherein R<1>, R<2>, R', R'', n, m and o are defined herein, or a pharmaceutically acceptable salt thereof.It has been found that the compounds of general formula I are adenosine receptor ligands with a good affinity to the A2A-receptor and a high selectivity to the A1- and A3 receptors. These compounds have useful pharmacological activities.
申请公布号 CL2004000761(A1) 申请公布日期 2005.02.04
申请号 CL20040000761 申请日期 2004.04.08
申请人 F. HOFFMANN-LA ROCHE AG. 发明人 ROGER DAVID NORCROSS
分类号 A61K31/428;A61P25/00;C07D207/34;C07D277/82;C07D319/12;C07D417/04;C07D417/14;C07D471/08;C07D491/10;(IPC1-7):A61K31/428 主分类号 A61K31/428
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