发明名称 N-oxides and derivatives of melphalan for treating diseased states associated with hypoxia inducible factor
摘要 This invention relates to compounds which are N-oxides and derivatives thereof, as well as their use to treat HIF related diseases. These compounds have the general formula set out below and are used to treat a variety of diseases associated with HIF: wherein R is an alkyl, aryl, arakyl or derivatives thereof such as CH3OCH2CH2-, CH3CH2OCH2CH2-, C6H5OCH2CH2-, C6H5CH2-, CH3(CH2)3OCH2CH2Cl; or any one of the following:
申请公布号 US2005026872(A1) 申请公布日期 2005.02.03
申请号 US20040929156 申请日期 2004.08.30
申请人 KIRKPATRICK LYNN;POWIS GARTH;WELSH SARAH J. 发明人 KIRKPATRICK LYNN;POWIS GARTH;WELSH SARAH J.
分类号 A61K31/195;A61K31/66;C07F9/6584;(IPC1-7):A61K31/66 主分类号 A61K31/195
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