发明名称 |
Method for quantitatively and/or qualitatively detecting layer thicknesses, a microreaction vessel and titre plate |
摘要 |
The invention relates to a method for quantitatively and/or qualitatively detecting layer thicknesses of biological or chemical molecules by means of ellipsometric measurements. Said molecules are deposited on at least one metal layer by virtue of interactions with a gaseous or liquid medium, whereby said metal layer is provided with an immobilisation layer. A method that can be carried out quickly is provided by including the surface plasmon resonance. Said method is provided with a significantly greater detection sensitivity and can be used not only for qualitatively detecting layers. According to the inventive method, the angle of incidence and/or the frequency of the electromagnetic radiation which is used for the ellipsometric measurements is/are adjusted in such a way that a surface plasmon resonance is produced in the metal layer. The detection sensitivity (deltacosDelta)/(thickness of the layer to be detected) is adjusted by means of the thickness of the metal layer.
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申请公布号 |
US2005025676(A1) |
申请公布日期 |
2005.02.03 |
申请号 |
US20030203121 |
申请日期 |
2003.08.14 |
申请人 |
EHRFELD WOLFGANG;WESTPHAL PETER;LIMBURG BERND;POMMEREAU ANTJE;BERGER SVEND |
发明人 |
EHRFELD WOLFGANG;WESTPHAL PETER;LIMBURG BERND;POMMEREAU ANTJE;BERGER SVEND |
分类号 |
G01B11/06;(IPC1-7):B01J19/00 |
主分类号 |
G01B11/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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