| 发明名称 |
LTA4 hydrolase inhibitors |
| 摘要 |
The invention relates to compounds which constitute a class of medicaments which have an anti-inflammatory activity and which act by inhibiting leukotriene A4 (LTA4), and enzyme which is responsible for the biosynthesis of leukotriene LTB4, a major proinflammatory mediator. The invention also relates to therapeutic anti-inflammatory, applications of these compounds as well as for methods of preparing these compounds.
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| 申请公布号 |
US2005027013(A1) |
申请公布日期 |
2005.02.03 |
| 申请号 |
US20040900384 |
申请日期 |
2004.07.28 |
| 申请人 |
DANVY DENIS;MONTEIL THIERRY;PLAQUEVENT JEAN-CHRISTOPHE;DUHAMEL PIERRE;DUHAMEL LUCETTE;NOEL NADINE;GROS CLAUDE;CHAMARD OLIVIER;SCHWARTZ JEAN-CHARLES;LECOMTE JEANNE-MARIE;PIETTRE SERGE |
发明人 |
DANVY DENIS;MONTEIL THIERRY;PLAQUEVENT JEAN-CHRISTOPHE;DUHAMEL PIERRE;DUHAMEL LUCETTE;NOEL NADINE;GROS CLAUDE;CHAMARD OLIVIER;SCHWARTZ JEAN-CHARLES;LECOMTE JEANNE-MARIE;PIETTRE SERGE |
| 分类号 |
A61K31/662;A61K31/085;A61K31/09;A61K31/198;A61K31/215;A61K31/223;A61K31/225;A61K31/27;A61K31/695;A61P1/16;A61P17/06;A61P19/02;A61P29/00;A61P43/00;C07C45/30;C07C47/277;C07C229/08;C07C229/22;C07C251/02;C07F9/38;C07F9/40;(IPC1-7):A61K31/137 |
主分类号 |
A61K31/662 |
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