发明名称 |
2-Aminothiazole allosteric enhancers of a ?1? adenosine receptors |
摘要 |
The present invention relates generally to a class of 2-aminothiazole derivatives which have recently been identified as allosteric enhancers of the A<custom-character file="US20050027125A1-20050203-P00900.TIF" wi="20" he="20" id="custom-character-00001"/>1? adenosine receptor. These compounds, and therapeutic compositions containing them, are useful for treating conditions in which activation of the A<custom-character file="US20050027125A1-20050203-P00900.TIF" wi="20" he="20" id="custom-character-00002"/>1? adenosine receptor would be beneficial, for example, those conditions in which stimulation of angiogenesis would improve blood flow to ischemic tissues.
|
申请公布号 |
US2005027125(A1) |
申请公布日期 |
2005.02.03 |
申请号 |
US20040499291 |
申请日期 |
2004.06.18 |
申请人 |
LINDEN JOEL;MACDONALD TIMOTHY L.;MURPHREE LAUREN;CHORDIA MAHENDRA D. |
发明人 |
LINDEN JOEL;MACDONALD TIMOTHY L.;MURPHREE LAUREN;CHORDIA MAHENDRA D. |
分类号 |
A61K31/428;A61P9/00;A61P9/06;A61P9/10;A61P15/08;A61P25/02;A61P25/20;A61P27/16;A61P29/00;A61P43/00;C07D277/60;C07D277/84;C07D417/04;(IPC1-7):C07D277/84 |
主分类号 |
A61K31/428 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|