NAPHTHALIN-CARBOXAMIDE ALS TACHYKININ REZEPTORANTAGONISTEN

摘要

A compound having the formula wherein R<1> is oxo, -OR, -OC(=O)R; or R<2> is H; or R<1> is -OR and R<2> is -OR; or R<1> and R<2> together form -O(CH2)mO-; and any pharmaceutically-acceptable salt thereof along with their use in treating depression, anxiety, asthma, rheumatoid arthritis, Alzheimer's disease, cancer, schizophrenia, oedema, allergic rhinitis, inflammation, pain, gastrointestinal-hypermotility, anxiety, emesis, Huntington's disease, psychoses including depression, hypertension, migraine, bladder hypermotility, or urticaria, along with methods of making the compounds and pharmaceutical compositions containing the compounds.