A COMPOSITION FOR DECREASING THE RISK OF LONG-HAUL TRAVELLER'S SYNDROME COMPRISING A MIXTURE OF PYCNOGENOL AND STANDARDIZED GIGER ROOT EXTRACT

摘要

Use of Pycnogenol<(R)> and standardized ginger extract in a well-defined proportion (e.g. 1:1.5) in a newly invented combination product as a Health care composition with the trade name Zinopin<(R)>, targeting Long-haul Traveller's Syndrome in passengers travelling by air, land or sea is described. The active ingredients work synergistically to reduce the risk of Deep Vein Thrombosis and/or oedema associated with or without motion sickness. The mechanism of action of the combination in Long-haul Traveller's Syndrome is discussed in light of the established physiological effects of both as Generally Recognized As Safe (GRAS) active components. The innovative steps towards the development of Zinopin<(R)> and preferred dosage ranges and forms are discussed.