CONTROLLED ABSORPTION OF MIXED THYROYD HORMONE FORMULATIONS

摘要

The invention relates to admixtures of the thyroid hormones and derivatives thereof. These admixtures, particularly L-thyroxine (T4) and liothyronine (T3), produce steady state or near steady state serum levels of (T3). When admixed in the appropriate ratio of (T4) to (T3), blood levels of (T3) hormone are maintained at a steady state for an extended period of time independent of the need for control release excipients. The change in the kinetics of (T3) absorption is controlled by the addition of (T4) to (T3).