| 发明名称 |
CERAMIDE DEPENDENT-STABILIZATION OF BACE1 |
| 摘要 |
The invention relates to methods and products for inhibiting ceramide associated Abeta accumulation. The invention is useful for screening compounds for such activity, as well as diagnosing, preventing, and treating Alzheimer's disease and other disorders associated with beta-secretase processing of substrates. |
| 申请公布号 |
WO2005009374(A2) |
申请公布日期 |
2005.02.03 |
| 申请号 |
WO2004US23476 |
申请日期 |
2004.07.21 |
| 申请人 |
THE GENERAL HOSPITAL CORPORATION;PUGLIELLI, LUIGI;KOVACS, DORA, M. |
发明人 |
PUGLIELLI, LUIGI;KOVACS, DORA, M. |
| 分类号 |
A01N1/00;A61K;C12Q1/68;G01N33/00;G01N33/50;G01N33/53;G01N33/567 |
主分类号 |
A01N1/00 |
| 代理机构 |
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