发明名称 |
3,5 DISUBSTITUTED INDAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR MEDIATING OR INHIBITING CELL PROLIFERATION |
摘要 |
3,5 disubstituted indazole compounds that modulate and/or inhibit cell proliferation, such as the activity of protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating CDK dependent diseases to modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, a nd to methods of treating cancer as well as other disease states associated wit h unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.
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申请公布号 |
CA2532908(A1) |
申请公布日期 |
2005.02.03 |
申请号 |
CA20042532908 |
申请日期 |
2004.07.19 |
申请人 |
PFIZER INC. |
发明人 |
MCALPINE, INDRAWAN JAMES;REICH, SIEGFRIED HEINZ;KEPHART, SUSAN ELIZABETH |
分类号 |
C07D413/04;A61K31/416;A61P35/00;C07D401/14 |
主分类号 |
C07D413/04 |
代理机构 |
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