METALLO PROTEINASE INHIBITORY AGENT

摘要

The present invention relates to an active agent, in particular a metalloproteinase inhibitory agent comprising casein-derived peptides obtained by hydrolysis of casein by a food grade bacteria. The invention also relates to the manufacture of a agent, in which a food grade bacteria of the genus Lactobacillus helveticus is contacted with casein in order to perform an hydrolysis and obtain casein-derivated peptides exhibiting metalloproteinases inhibitory property. The present invention also concern the isolated and purified inhibitory peptides obtained by hydrolysis of casein by the said bacteria.