Use of a dihydrojasmonic acid derivative as a desquamative agent

摘要

The cosmetic use of (dihydro)jasmonic acid derivatives (I), in which the keto function of the parent compound is replaced by optionally etherified or esterified hydroxy, alkylidene, amino, dihalo or ketal, as desquamating agents is new. Some of the compounds (I) are new. The cosmetic use of (dihydro)jasmonic acid derivatives of formula (I) (or their isomers, stereoisomers or salts) as desquamating agents is new. [Image] G : CH-OR a, CH-NRR', C=CR bR c, CH-CHRR', CYY' or C(OX)(OX'); R alinear, branched or cyclic, saturated or unsaturated 1-12C hydrocarbyl (optionally substituted (os) by 1-5 groups Q); -COR''; or -CO-R d; Q : OR'', OCOR'', SR'', SCOR'', NR''R''', NHCOR'', halo, CN or COOR''; R'', R''' : H, aryl or linear or branched, saturated or unsaturated 1-4C hydrocarbyl; R dalkyl, aryl, aralkyl or alkoxy of 1-17C (os by one or more of OH or OMe); R b, R cR or COOR e; R e1-4C hydrocarbyl; R, R' : H or linear, branched or cyclic, saturated or unsaturated 1-12C hydrocarbyl (os by 1-5 groups Q or COR''); or NRR' : heterocycle; X, X' : saturated or unsaturated 1-3C hydrocarbyl; or together form saturated or unsaturated 2-3C hydrocarbylene (os by 1-6C alkyl or aryl); Y, Y' : halo; R 1COOR, CONRR', CH 2OR, COR, CH 2R', SO 2OR, PO 3RR', NHR or NRR'; and R 2linear, branched or cyclic, saturated or unsaturated 1-18C hydrocarbyl (os by 1-5 groups Q or COR'') . Independent claims are included for (I; G = G') and (I; G = G''; R 1 = COOR) and their isomers, stereoisomers and salts as new compounds. G' : CH-OCOR' d, C=C(COOR e)R or CYY'; R dalkyl, aryl, aralkyl or alkoxy of 2-17C (os by one or more of OH or OMe); G'' : CH-OQ'; Q' : 1-6C linear or branched hydrocarbyl, substituted by one or more of OH, COOH and/or NH 2; R' 1COOQ; and Q : H or linear, branched or cyclic, saturated or unsaturated 1-12C hydrocarbyl.