发明名称 |
CYCLIPOSTINS, A METHOD FOR THEIR PRODUCTION AND THE USE OF THE SAME |
摘要 |
The invention relates to compounds of the general formula (I), wherein R<1>, R<2>, E, X1, X2 and X3 have the definitions in this application, obtained by the cultivation of the Streptomyces species HAG 004107 (DSM 13381) and to the physiologically compatible salts and chemical equivalents of said compounds. The invention also relates to a method for producing the cyclipostins and their physiologically compatible salts and chemical equivalents as medicaments, in particular as inhibitors of lipases, and to pharmaceutical preparations containing cyclipostin or a physiologically compatible salt or equivalent thereof. |
申请公布号 |
EP1280812(B1) |
申请公布日期 |
2005.02.02 |
申请号 |
EP20010936275 |
申请日期 |
2001.04.25 |
申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
VERTESY, LASZLO;EHRLICH, KLAUS;KURZ, MICHAEL;WINK, JOACHIM |
分类号 |
C12P17/18;A61K31/665;A61P3/10;A61P43/00;C07F9/6574;C12N1/20;C12P9/00;C12R1/465;(IPC1-7):C07F9/657 |
主分类号 |
C12P17/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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