发明名称 Substituted naphthoic acid derivatives useful in the treatment of insulin resistance and hyperglycemia
摘要 This invention provides compounds of Formula I having the structurewherein:R1 is hydroxyl, alkoxy of 1-4 carbons or -O(CH2)nX;n is an integer of 1-13;X is CONHR6 or CO2R6;R2 is hydrogen, halogen, hydroxyl, alkyl of 1-4 carbons, alkoxy of 1-4 carbons or acyl of 1-4 carbons;R3, R4 and R5 are each independently, hydrogen, halogen, hydroxyl, alkyl of 1-4 carbons, alkoxy of 1-4 carbons, acyl of 1-4 carbons, CF3, OCF3, SO2NHR6, NR6R7 or CO2R6;R6, and R7 are each independently, hydrogen, alkyl of 1-4 carbons, or alkylaryl where the aryl group is substituted with R2;or a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia.
申请公布号 US6849761(B2) 申请公布日期 2005.02.01
申请号 US20030656981 申请日期 2003.09.05
申请人 WYETH 发明人 MAYER SCOTT CHRISTIAN;KATZ ALAN HOWARD
分类号 C07C229/38;C07C311/37;(IPC1-7):C07C229/00 主分类号 C07C229/38
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