发明名称 |
METHOD FOR SYNTHESIZING PARA-HYDROQUINONE COMPOUND CONTAINING ALLYLIC SULFONE MOIETY AND USEFUL FOR PREPARATION OF COENZYME Q AND VITAMIN K, BY FIEDEL-CRAFTS REACTION |
摘要 |
<p>PURPOSE: Provided is a method for synthesizing a para-hydroquinone compound containing an allylic sulfone moiety by the one-stepwise Fiedel-Crafts reaction employing inexpensive and easily available starting materials with higher yield. CONSTITUTION: The para-hydroquinone compound containing an allylic sulfone moiety which can be efficiently utilized for the preparation of coenzyme Q and vitamin K, is represented by the formula 2, wherein R is OCH3 or a case in which R-R is CH=CH-CH=CH and P is an alkyl group having carbon atoms of 1 to 10, and is synthesized by the method comprising the Fiedel-Crafts reaction of a para-hydroquinone compound £A| containing a protecting group with (E)-4-halo-3-methyl-1-phenylsulfonyl-2-butene £E| or (E)-4-hydroxy-3-methyl-1-phenylsulfonyl-2-butene £F|.</p> |
申请公布号 |
KR20050011172(A) |
申请公布日期 |
2005.01.29 |
申请号 |
KR20030050157 |
申请日期 |
2003.07.22 |
申请人 |
KOO, SANG HO |
发明人 |
KOO, SANG HO;LEE, JUN SUP;MIN, JAE HONG;YANG, JAE DEUK |
分类号 |
C07C315/00;(IPC1-7):C07C315/00 |
主分类号 |
C07C315/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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