Immunogenic liposome compositions comprising vesicle forming lipids and an antigenic construct and methods of inducing an immune response using them

摘要

Described is an immunogenic liposome composition comprising vesicle-forming lipids and an antigenic construct comprising one or more antigenic determinants and a hydrophobic domain. Also described is a method of inducing an immunogenic response in a non human host animal, comprising administering an immunogenically effective amount of the immunogenic liposome composition comprising vesicle forming lipids, and an antigenic construct comprising one or more antigenic determinants and a hydrophobic domain wherein the hydrophobic domain has a surface area of greater than 500 Angstroms2 and is associated with the membrane of the liposome of the liposome composition. (62) Divided out of 510442