Methods of treatment using stabilized protein composition containing a protein such as G-CSF and a buffer such as HEPES

摘要

A method of treating or preventing infections in non-human mammals or in mammalian cells or tissue in vitro, comprising administering to the mammal or cells or tissue a therapeutically effective amount of a stabilized protein composition, wherein the stabilized protein composition comprises a protein and a stabilizing buffer, which composition is capable of maintaining therapeutic levels of such protein for a sustained period of at least about three days. Also disclosed is a method of maintaining therapeutic levels of a protein in a non-human mammal or in mammalian cells or tissue in vitro, for a sustained period, which comprises administering to the mammal or cells or tissue a stabilized protein composition, wherein the stabilized protein composition comprises a protein and a stabilizing buffer, which composition is capable of maintaining therapeutic levels of such protein for a sustained period of at least about three days.