ANTIGEN EPITOPES OF THE REGULATORY PROTEIN OF VIRULENCE FACTOR IN STAPHYLOCOCCUS AUREUS AND THEIR MIMOTOPES AND USE

摘要

This invention relates to two antigen epitopes of regulatory protein TRAP of virulence factor in staphylococcus aureus and their mimotopes. The sequence of the antigen epitope is NPTHQLFQFSASDT or SYFERYLYPIKE. The sequence of the mimotope is XPXHHQHXTGFT or SWFDXXLYPXXX, in which X is any one of 21 kinds of natural L type amino acids D type isomer. The antigen epitopes and their mimotope in this invention can be used to prepare a vaccine or medicine to resist staphylococcus aureus infection.