The invention is directed to biaryl compounds with two six membered rings fused wherein at least one six membered ring is substituted with a thiophenyl or furanyl ring. Useful in the inhibition of PKB kinase, the treatment of cancer, or the inhibition of tumor growth.
申请公布号
WO2005007099(A2)
申请公布日期
2005.01.27
申请号
WO2004US21834
申请日期
2004.07.09
申请人
IMCLONE SYSTEMS INCORPORATED;KAWAKAMI, JOEL;DUNCTON, MATTHEW;SHERMAN, DAN;HE, HAI-YING;KISELYOV, ALEXANDER;PYTOWSKI, BRONEK