| 发明名称 |
Glucagon-ähnliche insulinotrope Peptid-Analoge, Zusammensetzungen und Verwendungsverfahren |
| 摘要 |
Glucagon-like insulinotropic peptide (GLP-1(7-37)) analogs and derivatives are disclosed. The analogs include amino acid substitutions, amino and carboxyl terminal modifications, and C6-C10 acylations. The claimed compounds stimulate the secretion or biosynthesis of insulin in poorly functioning beta cells and are therefore useful in treating Type II diabetics |
| 申请公布号 |
DE69533868(D1) |
申请公布日期 |
2005.01.27 |
| 申请号 |
DE1995633868 |
申请日期 |
1995.10.13 |
| 申请人 |
ELI LILLY AND CO., INDIANAPOLIS |
发明人 |
CHEN, VICTOR JOHN;DIMARCHI, RICHARD D.;KRIAUCIUNAS, AIDAS V.;SMILEY, DAVID L.;STUCKY, RUSSELL D. |
| 分类号 |
A61K38/26;A61K38/00;A61P3/08;A61P3/10;C07K14/575;C07K14/605;C12N15/16;(IPC1-7):C12N15/16 |
主分类号 |
A61K38/26 |
| 代理机构 |
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