| 摘要 |
1346505 Cephalosporins BRISTOL-MYERS CO 19 April 1971 [27 March 1970] 24485/71 Heading C2A The invention comprises cephalosporins of general Formula I in which Z is a radical of Formula III or IV where R is alkyl, alkenyl or alkynyl having 1 to 5 carbon atoms. A process for the preparation of compounds of Formula I comprises reacting a compound of Formula II in which Y is 3 or 4-pyridyl, or a cationic salt thereof, with an alkylating, alkenylating or alkynylating agent. Pharmaceutical compositions having antibiotic properties comprise a compound of Formula I in conjunction with a carrier. A method of treating animals other than man, to cure them of diseases caused by grampositive or gram-negative bacteria comprises administering to the animal an effective dose of a compound of Formula I. |
