NOUVELLES SULFAGUANIDINES

摘要

1321541 Treating marek's disease MERCK & CO Inc 28 June 1971 [30 June 1970] 30255/ 71 Heading A5B [Also in Division C2] Pharmaceutical preparations especially suitable for treating or preventing Marek's disease occurring in poultry contain (I), (II), (III) and/or (IV) as active ingredient where Z signifies R 1 CH=N-, R 2 CONH- or (R 3 )(R 4 )(R 6 ). C.NH-, R 1 is phenyl containing F or alkylthio, or Cl and OH substituents or is a 5 or 6-membered ring heterocycle having 1 or 2 heteroatoms, R 2 is C 3 to 6 cycloalkyl, C 10 to 20 alkyl, CF 3 , a 5 or 6-membered ring heterocycle containing 1 heteroatom, alkoxy, haloalkoxy, alkoxyalkoxy or alkylthio, R 3 is NaSO 2 -, HO 2 C-CH 2 -S-, HO 2 C-CH (NHCOMe)CH 2 -S-, CH 3 COCH= or a radical (V), R 4 is H, alkyl or alkoxy, R 5 is H or alkyl and R 6 is H (R 6 is not present when R 3 is attached to C via a double bond). The preparations may be in the form of a feed, supplement, parenterally administrable solution, suspension or dispersion and may also contain nutrients and other additives, e.g. coccidiostats such as amprolium, ethopabate, nicarbazin and 1-(2-n-propyl-4-amino-5-pyridiminylmethyl)-2-methyl pyridinium chloride hydrochloride.