摘要 |
The invention provides a human PDE6B which is associated with the cardiovascular disorders, inflammatory diseases, metabolic diseases, hematological disorders, respiratory diseases, neurological disorders and urological disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, inflammatory diseases, metabolic diseases, hematological disorders, respiratory diseases, neurological disorders and urological disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of PDE6B as well as pharmaceutical compositions comprising such compounds. |
申请人 |
BAYER HEALTHCARE AG;GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS |
发明人 |
GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS |