摘要 |
FIELD: organic chemistry, chemical technology, medicine. ^ SUBSTANCE: invention relates to synthesis of new biologically active substance, namely, to gamma-hydroxypropylammonium-5-hydroxynicotinate of the formula (I): , eliciting an anti-ischemic, anti-arrhythmic and hypolipidemic activity. This compound shows low toxicity and absence of cardiodepressive effect. Compound of the formula (I) is prepared by interaction of 5-hydroxynicotinic acid with 3-amino-1-propanol in the presence of a solvent at heating. ^ EFFECT: valuable medicinal properties of compound. ^ 1 cl, 7 tbl, 3 ex |