| 摘要 |
PROBLEM TO BE SOLVED: To provide medicine particles for chewable type medicinal preparation of which the bitter taste suppressant effect is not damaged, even when it is molded into a chewable type medicinal solid preparation (particularly in tablet compression) and a method for producing the same, and chewable type medicinal solid preparation using the same and a method for producing the same. SOLUTION: Medicine-containing particles including bitter-tasting raw medical particles having an average particle size of 100-300μm, a grain size ratio (in mass ratio) of 75-425μm/less than 75μm = 60/40-100/0 and the aspect ratio (major axis/minor axis) of more than 90 mass % is 3/1-1/1, and a water insoluble polymer compound and a plasticizer are further coated with a water insoluble polymer compound and a plasticizer, thereby the chewable type medicinal solid preparation having film including water insoluble polymer compound is obtained. COPYRIGHT: (C)2005,JPO&NCIPI
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