发明名称 |
MODULATION OF PD-1 INTERACTIONS WITH ITS LIGANDS |
摘要 |
Disclosed are methods for downmodulating an immune response comprising contacting an immune cell with an agent that modulates the interaction between PD-1 and a PD-1 ligand (e.g., soluble forms of PD-1 or PD-1 ligand or antibodies to PD-1) to thereby modulate the immune response. |
申请公布号 |
ZA200308524(B) |
申请公布日期 |
2005.01.26 |
申请号 |
ZA20030008524 |
申请日期 |
2003.10.31 |
申请人 |
WYETH |
发明人 |
Beatriz M CARRENO;John LEONARD |
分类号 |
A61K;C12N15/09;A61K38/00;A61K38/17;A61K39/395;A61K45/00;A61K45/06;A61P25/28;A61P37/06;A61P43/00;C07K;C07K14/705;C07K16/28;C12N5/06 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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