发明名称 Crude extract from Viscum album coloratum, and proteins and lectins isolated therefrom
摘要 Disclosed is an extract from Korean mistletoe KM-110, which is of immunity enhancement and activity against tumor metastasis and can be used as an adjuvant material for vaccines applicable for the induction of humoral and cell-mediated immunity. Also disclosed are its fractions, a protein fraction KM-AS, a lectin fraction KML-C, lectin components KML-IIU and KML-IIL, which both are further purified from lectin fraction KML-C, a protein KMHBP which is obtained through heparin binding chromatography eluting with NaCl from a fraction C-free AS which is a portion of the KM-AS free of KML-C, and a mixture KM of the KMHBP and the KML-C. They are revealed as to their roles in the humoral and cell-mediated immunity enhancement and antitumoral activity.
申请公布号 US6846913(B1) 申请公布日期 2005.01.25
申请号 US20000627165 申请日期 2000.07.27
申请人 MISTLE BIOTECH CO., LTD. 发明人 KIM JONGBAE;SONG SEONGKYU;SUH BYUNGSUN;LEE KWANHEE;DOO MYOUNGSOOL;KWAK JINHWAN;SONG BYEOUNGDOO;YOON TAEKJOON;KANG TAEBONG;PARK CHOONHO
分类号 A61K36/8968;A61K38/00;A61P35/00;A61P35/04;A61P37/04;C07K14/415;(IPC1-7):A61K38/16;C07K14/00 主分类号 A61K36/8968
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