| 摘要 |
<p>Title cpd. of formula (I): and its Na and K salts (where R is (un)substd. aryl or aralkyl) is prepd. from corresp. benzyl penicillin I; R is benzyl; CO2H is CO2Y (Y is alkyl, (un)substd. benzyl, benzhydryl or (un)substd. phenethyl) which in water-immiscible org. solvent is reacted with chlorinating agent in presence tert. amine to form 6-(phenyl-acetochloroimide)-penicillanate which is then reacted to remove phenyl acetyl gp. to give (I).</p> |
