| 发明名称 |
INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND METHODS FOR IDENTIFYING THE SAME |
| 摘要 |
Inhibitors of MIF are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with MIF activity. The inhibitors of MIF have the following structures (Ia), (Ib) including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein n, R1, R2, R3, R4, X, and Z are as defined herein. Compositions containing an inhibitor of MIF in combination with a pharmaceutically acceptable carrier are also provided, as well as methods for use of the same. |
| 申请公布号 |
WO2004074218(A3) |
申请公布日期 |
2005.01.20 |
| 申请号 |
WO2004US04433 |
申请日期 |
2004.02.13 |
| 申请人 |
AVANIR PHARMACEUTICALS;SIRCAR, JAGADISH, C.;KUMAR, SUNIL, K., C.;YING, WENBIN |
发明人 |
SIRCAR, JAGADISH, C.;KUMAR, SUNIL, K., C.;YING, WENBIN |
| 分类号 |
A61K;A61K31/4709;A61K31/496;A61P29/00;A61P35/00;C07C;C07D215/54;C07D401/04;C07D401/12;C07D405/12;C07D409/12;C07D413/12;C07D417/12 |
主分类号 |
A61K |
| 代理机构 |
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