摘要 |
<p>An enoate reductase, cells containing the same, a preparation comprising the cells, or a culture obtained by culturing the cells is caused to act on a 4-halocrotonic acid derivative represented by the following general formula (I): to produce an optically active 4-halobutyric acid derivative represented by the following general formula (II). (In the formulae (I) and (II), R represents halogeno, nitro, hydroxy, optionally substituted alkyl, optionally substituted aryl, or optionally substituted alkoxy; X represents halogeno; and A1 and A2 each represents hydrogen or halogeno.)</p> |