OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF

摘要

This invention relates to new oxazolidin,41-es having a C" cl ropyl moiety, which are effective against aerobic and anerobic pathogen I esistant staphylococci, streptococci and enterococci, Bacteroides s Cl' idia spp. species, as well as acid-fast organisms such as Mycobacterium tuberculosis a nd other mycobacterial species. 10 The compounds are represented by structural formula (I): A a Rx (R4a)s Rx x 1 0 Ri Ar or HAr N 0 A /_R3 15 its enantiome r, diastereomer, or pharmaceutically acceptable salt or ester thereof.