| 发明名称 |
INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION |
| 摘要 |
There is provided a compound of formula (I), wherein X, Y, Z, R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptab le salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of microsomal prostaglandin E synthase-1 is desired and/or required, and particularly in the treatment of inflammation.< /SDOAB>
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| 申请公布号 |
CA2528626(A1) |
申请公布日期 |
2005.01.20 |
| 申请号 |
CA20042528626 |
申请日期 |
2004.07.09 |
| 申请人 |
BIOLIPOX AB |
发明人 |
KATKEVICS, MARTINS;KALVINS, IVARS;OLOFSSON, KRISTOFER;SUNA, EDGARS;PELCMAN, BENJAMIN;OZOLA, VITA;SCHAAL, WESLEY |
| 分类号 |
C07D403/04;A61K31/404;A61P29/00;C07D209/42;C07D401/04;C07D401/12;C07D403/12;C07D405/04;C07D405/14;C07D409/04 |
主分类号 |
C07D403/04 |
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