发明名称 |
Methods for determining optimal doses for a first investigational administration in humans |
摘要 |
The present invention provides a method for determining an optimal dose range of a compound for a first investigational administration of that compound in a human. The method involves stochastic simulation of allometric parameters to produce outcome distributions that provide a basis for selecting an optimal dose range. The present invention also provides optimal doses of compounds under clinical evaluation in the first administration of such compounds to humans.
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申请公布号 |
US2005015225(A1) |
申请公布日期 |
2005.01.20 |
申请号 |
US20040840197 |
申请日期 |
2004.05.06 |
申请人 |
GODFREY CHRISTOPHER J.;ROY AMIT;ETTE ENE I. |
发明人 |
GODFREY CHRISTOPHER J.;ROY AMIT;ETTE ENE I. |
分类号 |
G06F17/10;G06F19/00;(IPC1-7):G06F17/10 |
主分类号 |
G06F17/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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