IgM PRODUCTION BY TRANSFORMED CELL AND METHOD OF QUANTIFYING THE SAME
摘要
<p>Pentamer IgM can be obtained by locating genes respectively encoding H chain, L chain and J chain on a single vector and then transforming into an appropriate host cell. The gene encoding J chain may be transferred via cotransformation. In the case where the J chain is not expressed, the product is obtained as hexamer IgM. The transformant thus obtained shows a high IgM productivity. It is also intended to provide a method whereby a polymer IgM can be separated and quantified.</p>