发明名称 IgM PRODUCTION BY TRANSFORMED CELL AND METHOD OF QUANTIFYING THE SAME
摘要 <p>Pentamer IgM can be obtained by locating genes respectively encoding H chain, L chain and J chain on a single vector and then transforming into an appropriate host cell. The gene encoding J chain may be transferred via cotransformation. In the case where the J chain is not expressed, the product is obtained as hexamer IgM. The transformant thus obtained shows a high IgM productivity. It is also intended to provide a method whereby a polymer IgM can be separated and quantified.</p>
申请公布号 WO2005005636(A1) 申请公布日期 2005.01.20
申请号 WO2004JP10444 申请日期 2004.07.15
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA;IRIE, REIKO;TSUNODA, HIROYUKI;IGAWA, TOMOYUKI;SEKIMORI, YASUO;TSUCHIYA, MASAYUKI 发明人 IRIE, REIKO;TSUNODA, HIROYUKI;IGAWA, TOMOYUKI;SEKIMORI, YASUO;TSUCHIYA, MASAYUKI
分类号 C07K16/00;C07K16/30;C12N15/13;G01N33/68;(IPC1-7):C12N15/13;G01N27/447;C12P21/02;C07K16/18;G01N33/53;G01N33/561;A61K39/395;C12N5/10 主分类号 C07K16/00
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