发明名称 |
BENZIMIDAZOLE CARBOXAMIDES AS RAF KINASE INHIBITORS |
摘要 |
The present invention relates to benzimidazole carboxamides of formula (I), the use of the compounds of formula (I) as inhibitors of as inhibitors of on e or more kinases, the use of the compounds of formula (I) for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said pharmaceutical composition to a patient. Accordingly, the compound of Formula (I) or a pharmaceutically acceptable salt thereof is administered for the treatment of diseases mediated by one or more kinase phathways, preferably by the raf kinase pathway, especially cancers.
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申请公布号 |
CA2531856(A1) |
申请公布日期 |
2005.01.20 |
申请号 |
CA20042531856 |
申请日期 |
2004.06.11 |
申请人 |
MERCK PATENT GMBH |
发明人 |
BUCHSTALLER, HANS-PETER;AMENDT, CHRISTIANE;ZENKE, FRANK;GRELL, MATTHIAS;WIESNER, MATTHIAS;SIRRENBERG, CHRISTIAN |
分类号 |
A61K31/4184;A61K31/4439;A61K31/506;A61P35/00;C07D401/12;C07D403/12 |
主分类号 |
A61K31/4184 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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